Eden Openly Editorial
Evidence Reviews
Comprehensive, transparent reviews of the evidence underpinning transgender healthcare, clinical practice and health policy. Every review documents the available evidence, its strengths and limitations, and where uncertainty remains.
What is an Evidence Review?
Evidence Reviews are comprehensive syntheses of the available literature. They examine the quality of the evidence, discuss strengths and limitations, distinguish evidence from inference, and identify where uncertainty remains.
- Comprehensive review of the literature.
- Full references and methodology.
- Transparent discussion of strengths and limitations.
- Updated as evidence evolves.
Evidence Reviews and Evidence Notes
Evidence Notes provide a concise five-minute summary of the evidence for clinicians, journalists and policymakers.
Evidence Reviews provide the full supporting analysis, methodology and references behind those summaries.
Most Evidence Notes published by Eden Openly are supported by a companion Evidence Review, allowing readers to inspect the evidence, assumptions and limitations behind our conclusions. Standalone notes, which have no matching review, are marked in the list below.
Published Evidence Reviews
Our published Evidence Reviews, with more to follow:
- ER-001
The First Five Minutes of Care - ER-002
Readiness, not diagnosis - ER-003
Chosen Names and Pronouns - ER-004
Healthcare Avoidance - ER-005
Feminising Hormone Therapy - ER-006
Skin Effects of Oestrogen in Transfeminine People - ER-007
Masculinising Hormone Therapy - ER-008
Hormone Monitoring & Target Ranges - ER-009
Anti-androgens Compared - ER-010 – 012
Unused — review numbers held so each Evidence Review stays paired by number with its companion Evidence Note; the notes published at EN-010–012 are standalone, without matching reviews. - ER-013
5α-reductase Inhibitors: Finasteride and Dutasteride in Feminising Therapy - ER-014
Puberty Suppression in Adolescents - ER-015
Masculinising and Feminising Hormones in Adolescents - ER-018
Venous Thromboembolism, Myocardial Infarction and Ischaemic Stroke in Feminising Hormone Therapy - ER-023
Erythrocytosis and Raised Haematocrit in Testosterone Therapy
Published in two parts — the review, and its correction record, which is a companion page rather than a section. Zenodo deposit pending. - ER-025
Unused — there is no Evidence Review ER-025. The number is held so that reviews and notes stay paired by number; the note published at EN-025, Five numbers, five ways of counting, is a standalone Evidence Note, without a matching review.
Editorial Principles
- Evidence before opinion.
- Transparency over certainty.
- Clearly distinguish evidence from inference.
- Document uncertainty rather than conceal it.
- Update reviews when significant new evidence emerges.
Related publication types
- Evidence Notes — concise evidence summaries.
- Editorial Briefings — timely analysis of current issues.
- Clinical Reviews — long-form clinical analysis.
- Editorial Standards — the standards that guide our publishing.